Distribution agreement for uniform iron oxide NPs

IOLITEC and MagnnPro, LLC have put an agreement for the distribution of MagnnPro's highly uniform nano iron oxide products into effect. These highly uniform iron oxide nanospheres, nanocubes and nanoparticle conjugation kits are now availale through IOLITEC nanomaterials.

DP-1111-HP-0001 Organic Nanospheres  

Highly uniform nanospheres that come as a dark brown color dispersed in organic solvent (chloroform).
Concentration: 1 mg/mL
Volume: 20 mL 
Size/Variation: 12 ± 2 nm

DP-1112-HP-0001 Organic Nanocubes

Highly uniform nanocubes that come as a dark brown color dispersed in organic solvent (chloroform).
Concentration: 1 mg/mL
Volume: 20 mL 
Size/Variation: 12 ± 2 nm

DP-1113-HP-0001 Water Soluble Nanospheres

Highly uniform nanospheres that come as a dark brown color dispersed in DI water. Particle surface has amine coating and can be easily dispersed in other polar solutions.
Concentration: 1 mg/mL
Volume: 20 mL 
Size/Variation: 12 ± 2 nm

DP-1114-HP-0001 Water Soluble Nanocubes

Highly uniform nanocubes that come as a dark brown color dispersed in DI water. Particle surface has amine coating and can be easily dispersed in other polar solutions.
Concentration: 1 mg/mL
Volume: 20 mL 
Size/Variation: 12 ± 2 nm

DP-1115-HP-0001 Conjugation Kits

Simple kit consisting of our nanoparticles that enable you to perform linker free conjugation with various ligands, i.e. proteins, peptides, small molecules, polymers, and DNA. Please see our included SOP for reference molecules and steps of conjugation.
Concentration: 1 mg/mL
Volume: 20 mL 
Size/Variation: 12 ± 2 nm

NO-1116-HP-0001 Nano Powder

Dark black iron oxide powder
Unit Amount: 20 mg
Size/Variation: 12 ± 2 nm

To learn more about these products, please continue reading MagnnPro's newsletter below or contact Diese E-Mail-Adresse ist gegen Spambots geschützt! JavaScript muss aktiviert werden, damit sie angezeigt werden kann. .

 

MagnnPro, LLC is a high-tech start-up company that has its origins in the Chemical and Biological Engineering laboratory at The University of Alabama. Founded in May, 2012 the company is housed in the Alabama Institute for Manufacturing Excellence (AIME) building, a state-of-the art facility. MagnnPro, LLC is run by a chief executive officer and experienced researchers. We anticipate fast company growth as a result of patent protected technology; which provides an advantage over current technology, all at a competitive price.

 

MagnnPro mainly produces four categories of iron oxide based products, including Nanoparticle Conjugation Kits, uniform and shape controlled water soluble nanoparticles, organic soluble nanoparticles, and nano powders.

TEM images of MagnnPro’s uniform and shape controlled iron oxide nanomaterials 

Figure 1. TEM images of MagnnPro’s uniform and shape controlled iron oxide nanomaterials

Nanoparticle conjugation kits consist high quality magnetic nanoparticles with a uniquely designed functional surface. The nanoparticles prepared for each of our kits will be produced using a newly modified heat-up method developed in house. This method allows the production of iron oxide nanoparticles with great control over nanoparticle size, shape, and size distribution. The uniquely designed functional surfaces of the nanoparticles allow facile conjugation of chemical and biological molecules (DNA, protein, etc.), without the need for any type of chemical linkers. The kits will have the capability to be specifically designed to meet the detailed needs of potential customers in nanobiotechnology. Our products have demonstrated the ability to effectively attach large proteins (e.g., antibody, albumin), short peptides (glutathione), chemicals (histamine), and polymers (amine-terminated polyethylenegltcol) onto nanoparticle surfaces. Each kit contains easy operating instructions to perform the conjugation without the need for prior training or advanced degrees (Fig. 2).

 Applications of MagnnPro’s Kits

Figure 2. Applications of MagnnPro’s Kits

Nanomaterial in water, in organic solvents, and as a powder - MagnnPro also manufactures and sells iron oxide nanomaterials in different shapes, different solvent media, and with different solubility capabilities, for those who do not need the functionality of the amine coated kits. Unlike the currently commercially available iron oxide nanoparticles produced from a co-precipitation method, generating nanoparticles with wide size distribution and uncontrolled magnetic properties. MagnnPro’s uniquely designed and patented procedure allows for the functionalization of high quality magnetic nanoparticles with dopamine molecules. Once activated the dopamine groups can directly interact with biological molecules containing amine and/or thiol groups through Michael addition and/or Schiff base formation. The particles are made at an average size of 12 nm ± 2. MagnnPro has the capability to make different sizes (between 4 nm – 50 nm). The distinct advantage of this approach is the elimination of the use of chemical linkers during conjugation, which significantly simplifies the conjugation process, reduces the requirements of well-trained personnel, and increases the conjugation efficiency (Fig. 3). To make the iron oxide particles adaptable to medical applications, such as drug delivery and as contrast agent for MRI, MagnnPro has made the particles water soluble, this work has been highlighted in Nature.

 Potential applications of MagnnPro’s functionalized nanomaterial

Figure 3. Potential applications of MagnnPro’s functionalized nanomaterial with publication references

MagnnPro Videos

MagnnPro – MRI T1 Contrast Agent:    https://www.youtube.com/watch?v=TFBhQLDHOQY

MagnnPro – Nanoconjugation Kits:   https://www.youtube.com/watch?v=f-JVhm8Vxqo

MagnnPro – MALDI Matrix:   https://www.youtube.com/watch?v=B83ETN2S0zA

 

  MagnnPro Articles


http://www.nature.com/nature/journal/v476/n7358/full/476009e.html

http://pubs.rsc.org/en/Content/ArticleLanding/2014/TB/c4tb00840e#!divAbstract

http://pubs.acs.org/doi/abs/10.1021/la301200g

http://pubs.rsc.org/en/Content/ArticleLanding/2014/NR/c3nr06040c#!divAbstract

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